In the Lazio region , several pilgrimage routes lead to significant religious and historical sites, often connected to the tradition of pilgrimage to Rome, the heart of the Catholic Church. Here are some notable pilgrimage routes in Lazio:

The Via Francigena in Lazio: This segment of the Via Francigena traverses Lazio on its way to Rome. Pilgrims pass through picturesque towns and countryside, including important stops like Viterbo, known for its well-preserved medieval town center and its significance in medieval politics and religion; Sutri, with its ancient amphitheater and Etruscan tombs; and Montefiascone, famous for its wine and panoramic views.

The Via Francigena del Sud: After reaching Rome, some pilgrims continue their journey southward through the Via Francigena del Sud towards the ports of Apulia, from where they could sail to the Holy Land or to the sanctuary of Monte Sant'Angelo. While not as well-documented or popular as its northern counterpart, this route offers a journey through the less-traveled landscapes of southern Lazio and beyond.

The Cammino di San Benedetto: This route connects Norcia, the birthplace of Saint Benedict, to Montecassino, where he established one of his first monasteries. Though the majority of this route lies outside Lazio, it culminates in the region at the Abbey of Montecassino, one of the most important sites of Christian pilgrimage, due to its historical significance and its role in the spread of Benedictine monasticism.

The Marian Sanctuaries Route: This itinerary links several sanctuaries dedicated to the Virgin Mary scattered throughout Lazio. Notable stops include the Sanctuary of Our Lady of Good Counsel in Genazzano, the Shrine of Our Lady of the Oak in Viterbo, and the Sanctuary of Madonna del Divino Amore near Rome. Each site has its own unique history and significance, offering a deep dive into Marian devotion in the region.

The Sanctuary of the Holy Face of Jesus in Manoppello: Though the main sanctuary is in Abruzzo, the pilgrimage to the Holy Face often includes stops in Lazio at significant religious sites en route to Manoppello. Pilgrims can visit churches and monasteries that honor the Veil of Veronica, which is said to bear the face of Jesus, similar to the relic housed in Manoppello.

These routes through Lazio offer a blend of spiritual journey, historical exploration, and natural beauty, attracting pilgrims and travelers with varied interests.